Correlates of Cytotoxic T Lymphocyte Vaccine-Induced Control Against Simian Immunodeficiency Virus (SIV)

HMA Mohammad - 2018 - search.proquest.com
levels of virus-specific CD8 + T cells in follicular areas of lymphoid tissues. I determined
the location, abundance, and phenotype of virus-specific … upper female reproductive tract (uterus

The importance of semen leukocytes in HIV-1 transmission and the development of prevention strategies

M Cavarelli, R Le Grand - Human Vaccines & Immunotherapeutics, 2020 - Taylor & Francis
… the life expectancy of HIV-1 infected individuals; however, there … Indeed, virus-specific T cells
in the semen do not control … A dual chamber model of female cervical mucosa for the study …

T lymphocyte inhibitory/exhaustion marker expression in chronic HIV-1 infection and the impact of TB co-infection

M Golden - 2016 - scholar.sun.ac.za
… which ultimately induces T lymphocyte exhaustion. Co-… two component study, a total of
101 HIV-1 infected, 25 HIV-1-… showed that pregnant women expressed lower levels of HLA-…

Human immunodeficiency virus infection promotes human papillomavirus-mediated anal squamous carcinogenesis: an immunologic and pathobiologic review

O Bushara, K Krogh, SE Weinberg, BS Finkelman… - Pathobiology, 2022 - karger.com
… contribute to CD8+ T lymphocyte exhaustion by upregulating … The anal canal mirrors the
milieu of the cervix, which is … immune cells may generate productive levels of the Tat protein. Tat …

Impact of HIV-1 infection on the feto-maternal crosstalk and consequences for pregnancy outcome and infant health

M Altfeld, MJ Bunders - Seminars in immunopathology, 2016 - Springer
… and cART in HIV-1-infected women on pregnancy outcomes … , proliferation, and expansion
of virus-specific T cells [25]. T … homing to the placenta and uterus. This process particularly …

[HTML][HTML] A mature macrophage is a principal HIV-1 cellular reservoir in humanized mice after treatment with long acting antiretroviral therapy

M Araínga, B Edagwa, RL Mosley, LY Poluektova… - Retrovirology, 2017 - Springer
… within CD4 + T lymphocyte compartments after ART … Total cell DNA and RNA obtained from
the HIV-1 infected … is limitations in recruitment of virus-specific cytotoxic T lymphocytes. Both …

[HTML][HTML] Persistence of viral RNA in lymph nodes in ART-suppressed SIV/SHIV-infected Rhesus Macaques

AM Cadena, JD Ventura, P Abbink… - Nature …, 2021 - nature.com
… Low levels of viral DNA were also detected in the cervix, lungs… groups, the highest levels
of virus-specific T cell responses … If these findings translate to HIV-1-infected humans, they …

[HTML][HTML] The role of innate immunity in natural elite controllers of HIV-1 infection

Y Shi, J Su, R Chen, W Wei, Z Yuan, X Chen… - Frontiers in …, 2022 - frontiersin.org
… of HIV infection, HIV-1-infected natural elite controllers are a … ), and maintain a CD4+ T
lymphocyte count at a normal level (>… shedding in the cervix of HIV-infected women, suggesting …

[HTML][HTML] ART influences HIV persistence in the female reproductive tract and cervicovaginal secretions

R Olesen, MD Swanson, M Kovarova… - The Journal of …, 2016 - Am Soc Clin Investig
… decrease the genital levels of HIV in both men and women (15–… percentage of cervical CD4
+ T cells than infected women not … The antibody clones included in the flow cytometry panels …

[HTML][HTML] Innate invariant NKT cell recognition of HIV-1infected dendritic cells is an early detection mechanism targeted by viral immune evasion

D Paquin-Proulx, A Gibbs, SM Bächle… - The Journal of …, 2016 - journals.aai.org
… and cervical mucosa were obtained from women undergoing … B virusspecific immunity in
mice. Our finding that iNKT cells respond to HIV-1 infection by recognition of elevated levels of …